In the research training group, R-loop Regulation in Robustness and Resilience (4R), we are committed to investigating the intricate mechanisms through which R-loop regulation exerts its influence on biological systems. Our primary focal points include: the orchestration of genome stability, encompassing DNA repair and telomere maintenance, as well as Gene regulation and RNA processing. Our 14 participating research groups have a strong research record in the R-loop and RNA Biology fields, which is underlined by strong publications in leading scientific journals.

We offer fully funded PhD positions, a vibrant interdisciplinary research environment, highly specialized seminar series and tech talks, training courses that develop both scientific and complementary skills, and a strong international PhD student community within the IPP. Our methodological focus lies on cutting-edge genome-wide mapping methodologies integrated with state-of-the-art proteomics, microscopy, and contemporary analytical techniques. We hope to inspire an academic trajectory for our students, giving them tools to thrive in academia and beyond. The GRK2859 “4R-RTG” is funded by the DFG (Deutsche Forschungsgemeinschaft – German Research Foundation.)