![](https://4r-rtg.de/wp-content/uploads/manual/Tim_IMG_20231215_110354_1.jpg)
Tim Preißendörfer
- Institute of Molecular Biology Mainz
- Julian König lab
- Project 11. The interplay between RNA splicing and R-loop formation
- German
“R-loops are fascinating because of their impact on gene expression and many unknown aspects to investigate.”
the interplay between RNA splicing and R-loop formation, particularly in the context of pathologies such as cancer. Mutation or inhibition of core splicing factors has been shown to trigger R-loop accumulation. The study will focus on characterising the direct effects of RNA splicing on R-loop formation and the mechanistic link between them. Various techniques such as CRISPR/Cas9 genome editing and DRIP-seq experiments will be used to gain insight into the molecular processes involved.
I enjoy motorcycling, mycology, video games.
2021 – 2023: Technical University of Darmstadt.
2016 – 2019: Technical University of Darmstadt.
Publications
work in progress...