Pauline Ott
- Johannes Gutenberg University of Mainz
- Peter Baumann lab
- Project 1. R-loops modulating telomere maintenance and life span in fission yeast
- German
“I decided to work with the R-loops because I am fascinated by their dual role in genome regulation, particularly in the telomeric region.”
the intriguing interplay between telomeric transcription and chromosome end maintenance. By manipulating the different types of RNA transcribed from telomeres and studying the formation of R-loops and RNA:DNA hybrids, we aim to improve our understanding of their role in telomere elongation, especially in the presence of an active telomerase. In addition, the project challenges the conventional separation between telomere maintenance by telomerase and recombination and seeks to better understand both their individual and potential joint contributions to telomere elongation.
I enjoy drawing, hiking, going to the gym, and playing board games.
2019 – 2021: MSc in Molecular Biomedicine, Heinrich-Heine University Düsseldorf, Germany.
2015 – 2019: BSc in Biology, Heinrich-Heine University Düsseldorf, Germany.