Rosa Hererra Rodrigues
- Institute of Molecular Biology Mainz
- Jan Padeken lab
- Project 13. Regulation and specificity of RNase H1 enzymes.
- Spanish
“R-loops can have a wide range of functions and effects. I want to better understand why R-loops at some repetitive sequences are a source of genome instability.”
the pathways responsible for the de novo establishment of H3K9me2/3 in C. elegans, a process crucial for preventing the harmful effects of unregulated transcription. Without proper regulation, the transcription of repetitive elements can lead to the accumulation of toxic R-loops and genomic instability. We aim to understand why transcription at some repetitive elements result in R-loop formation and if there is a feedback loop between R-loops/genomic instability and heterochromatin establishment.
I like reading, plants, many crafts and enjoying time with friends.
2020 – 2021: Genetics and Genomics, University of Barcelona, Spain.
2016 – 2020: Biotechnology, University of Barcelona, Spain.