Zukhra Stamgaliyeva
- Johannes Gutenberg University of Mainz
- Brian Luke lab
- Project 4. Understanding RNase H1 regulation at telomeres and beyond
- Kazakh
“I chose to work with R-loops because, after my master’s degree, I had the opportunity to work on RNA modifications within R-loops in cancer cells. This experience deepened my interest in understanding how these RNA-DNA hybrids influence genome stability. It was a natural step to explore how R-loops impact genomic integrity, not just in cancer but also in the context of aging, where cellular stability is crucial.”
the role of R-loops – RNA: DNA hybrid structures – in the aging process, using Saccharomyces cerevisiae as a model organism. By exploring how R-loops contribute to genomic instability over time, I aim to find mechanisms that may drive age-related cellular damage. Ultimately, my work is about understanding the molecular mechanisms that link genomic instability to aging, with a focus on the role of R-loops.
i like exploring new cuisines and recipes, hiking, snowboarding newcommer.
2018-2020: MSc from the Eurasian National University, Astana, Kazakhstan
2018: BSc from the Eurasian National University, Astana, Kazakhstan